- Saint Martin
- Sallis
- Saltillo
- Sandersville
- Sardis
- Satartia
- Saucier
- Schlater
- Scooba
- Sebastopol
- Seminary
- Senatobia
- Shannon
- Sharon
- Shaw
- Shelby
- Sherman
- Shubuta
- Shuqualak
- Sidon
- Silver City
- Silver Creek
- Slate Spring
- Sledge
- Smithville
- Snow Lake Shores
- Soso
- Southaven
- Standing Pine
- Starkville
- State Line
- Stonewall
- Sturgis
- Summit
- Sumner
- Sumrall
- Sunflower
- Sylvarena
